Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or...
Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer (MOUNTAINEER): a multicentre, open-label, phase 2 study
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Author / Creator
MOUNTAINEER investigators , Strickler, John H, MD , Cercek, Andrea, MD , Siena, Salvatore, Prof , André, Thierry, Prof , Ng, Kimmie, MD , Van Cutsem, Eric, Prof , Wu, Christina, Prof , Paulson, Andrew S, MD , Hubbard, Joleen M, MD , Coveler, Andrew L, MD , Fountzilas, Christos, MD , Kardosh, Adel, MD , Kasi, Pashtoon M, MD , Lenz, Heinz-Josef, Prof , Ciombor, Kristen K, MD , Elez, Elena, MD , Bajor, David L, MD , Cremolini, Chiara, MD , Sanchez, Federico, MD , Stecher, Michael, MD , Feng, Wentao, PhD and Bekaii-Saab, Tanios S, Prof
Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
SummaryBackgroundHER2 is an actionable target in metastatic colorectal cancer. We assessed the activity of tucatinib plus trastuzumab in patients with chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer. MethodsMOUNTAINEER is a global, open-label, phase 2 study that enrolled patients aged 18 years and...
Alternative Titles
Full title
Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer (MOUNTAINEER): a multicentre, open-label, phase 2 study
Authors, Artists and Contributors
Author / Creator
Strickler, John H, MD
Cercek, Andrea, MD
Siena, Salvatore, Prof
André, Thierry, Prof
Ng, Kimmie, MD
Van Cutsem, Eric, Prof
Wu, Christina, Prof
Paulson, Andrew S, MD
Hubbard, Joleen M, MD
Coveler, Andrew L, MD
Fountzilas, Christos, MD
Kardosh, Adel, MD
Kasi, Pashtoon M, MD
Lenz, Heinz-Josef, Prof
Ciombor, Kristen K, MD
Elez, Elena, MD
Bajor, David L, MD
Cremolini, Chiara, MD
Sanchez, Federico, MD
Stecher, Michael, MD
Feng, Wentao, PhD
Bekaii-Saab, Tanios S, Prof
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2810922249
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2810922249
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(23)00150-X
