Molecular mechanisms of gasdermin D pore-forming activity
Molecular mechanisms of gasdermin D pore-forming activity
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
The regulated disruption of the plasma membrane, which can promote cell death, cytokine secretion or both is central to organismal health. The protein gasdermin D (GSDMD) is a key player in this process. GSDMD forms membrane pores that can promote cytolysis and the release of interleukin-1 family cytokines into the extracellular space. Recent disco...
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Full title
Molecular mechanisms of gasdermin D pore-forming activity
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TN_cdi_proquest_miscellaneous_2823041008
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2823041008
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-023-01526-w
