BRAF–MEK Inhibition in Newly Diagnosed Papillary Craniopharyngiomas
BRAF–MEK Inhibition in Newly Diagnosed Papillary Craniopharyngiomas
About this item
Full title
Author / Creator
Brastianos, Priscilla K. , Twohy, Erin , Geyer, Susan , Gerstner, Elizabeth R. , Kaufmann, Timothy J. , Tabrizi, Shervin , Kabat, Brian , Thierauf, Julia , Ruff, Michael W. , Bota, Daniela A. , Reardon, David A. , Cohen, Adam L. , De La Fuente, Macarena I. , Lesser, Glenn J. , Campian, Jian , Agarwalla, Pankaj K. , Kumthekar, Priya , Mann, Bhupinder , Vora, Shivangi , Knopp, Michael , Iafrate, A. John , Curry, William T. , Cahill, Daniel P. , Shih, Helen A. , Brown, Paul D. , Santagata, Sandro , Barker, Fred G. and Galanis, Evanthia
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Genetic analysis has shown the presence of activating
BRAF
mutations in 94% of papillary craniopharyngiomas. A phase 2 study showed partial response or better in 15 of 16 previously untreated patients.
Alternative Titles
Full title
BRAF–MEK Inhibition in Newly Diagnosed Papillary Craniopharyngiomas
Authors, Artists and Contributors
Author / Creator
Twohy, Erin
Geyer, Susan
Gerstner, Elizabeth R.
Kaufmann, Timothy J.
Tabrizi, Shervin
Kabat, Brian
Thierauf, Julia
Ruff, Michael W.
Bota, Daniela A.
Reardon, David A.
Cohen, Adam L.
De La Fuente, Macarena I.
Lesser, Glenn J.
Campian, Jian
Agarwalla, Pankaj K.
Kumthekar, Priya
Mann, Bhupinder
Vora, Shivangi
Knopp, Michael
Iafrate, A. John
Curry, William T.
Cahill, Daniel P.
Shih, Helen A.
Brown, Paul D.
Santagata, Sandro
Barker, Fred G.
Galanis, Evanthia
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2836878192
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2836878192
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2213329
