Distinct transcriptomic responses to Aβ plaques, neurofibrillary tangles, and APOE in Alzheimer's di...
Distinct transcriptomic responses to Aβ plaques, neurofibrillary tangles, and APOE in Alzheimer's disease
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United States: John Wiley & Sons, Inc
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Language
English
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Publisher
United States: John Wiley & Sons, Inc
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Contents
INTRODUCTION
Omics studies have revealed that various brain cell types undergo profound molecular changes in Alzheimer's disease (AD) but the spatial relationships with plaques and tangles and APOE‐linked differences remain unclear.
METHODS
We performed laser capture microdissection of amyloid beta (Aβ) plaques, the 50 μm halo around them,...
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Full title
Distinct transcriptomic responses to Aβ plaques, neurofibrillary tangles, and APOE in Alzheimer's disease
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TN_cdi_proquest_miscellaneous_2839250991
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2839250991
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ISSN
1552-5260,1552-5279
E-ISSN
1552-5279
DOI
10.1002/alz.13387