Molecular pathway of mitochondrial preprotein import through the TOM–TIM23 supercomplex
Molecular pathway of mitochondrial preprotein import through the TOM–TIM23 supercomplex
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Author / Creator
Zhou, Xueyin , Yang, Yuqi , Wang, Guopeng , Wang, Shanshan , Sun, Dongjie , Ou, Xiaomin , Lian, Yuke and Li, Long
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Over half of mitochondrial proteins are imported from the cytosol via the pre-sequence pathway, controlled by the TOM complex in the outer membrane and the TIM23 complex in the inner membrane. The mechanisms through which proteins are translocated via the TOM and TIM23 complexes remain unclear. Here we report the assembly of the active TOM–TIM23 su...
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Full title
Molecular pathway of mitochondrial preprotein import through the TOM–TIM23 supercomplex
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TN_cdi_proquest_miscellaneous_2864157307
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2864157307
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/s41594-023-01103-7