Reflux conditions induce E-cadherin cleavage and EMT via APE1 redox function in oesophageal adenocar...
Reflux conditions induce E-cadherin cleavage and EMT via APE1 redox function in oesophageal adenocarcinoma
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Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
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Language
English
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Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
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Contents
ObjectiveChronic gastro-oesophageal reflux disease, where acidic bile salts (ABS) reflux into the oesophagus, is the leading risk factor for oesophageal adenocarcinoma (EAC). We investigated the role of ABS in promoting epithelial-mesenchymal transition (EMT) in EAC.DesignRNA sequencing data and public databases were analysed for the EMT pathway en...
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Full title
Reflux conditions induce E-cadherin cleavage and EMT via APE1 redox function in oesophageal adenocarcinoma
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TN_cdi_proquest_miscellaneous_2868120872
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2868120872
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ISSN
0017-5749,1468-3288
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2023-329455
