Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholang...
Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholangiocarcinoma of different etiologies
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Author / Creator
Hong, Jing Han , Yong, Chern Han , Heng, Hong Lee , Chan, Jason Yongsheng , Lau, Mai Chan , Chen, Jianfeng , Lee, Jing Yi , Lim, Abner Herbert , Li, Zhimei , Guan, Peiyong , Chu, Pek Lim , Boot, Arnoud , Ng, Sheng Rong , Yao, Xiaosai , Wee, Felicia Yu Ting , Lim, Jeffrey Chun Tatt , Liu, Wei , Wang, Peili , Xiao, Rong , Zeng, Xian , Sun, Yichen , Koh, Joanna , Kwek, Xiu Yi , Ng, Cedric Chuan Young , Klanrit, Poramate , Zhang, Yaojun , Lai, Jiaming , Tai, David Wai Meng , Pairojkul, Chawalit , Dima, Simona , Popescu, Irinel , Hsieh, Sen-Yung , Yu, Ming-Chin , Yeong, Joe , Kongpetch, Sarinya , Jusakul, Apinya , Loilome, Watcharin , Tan, Patrick , Tan, Jing and Teh, Bin Tean
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title
Language
English
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Publication information
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Subjects
More information
Scope and Contents
Contents
ObjectivesCholangiocarcinoma (CCA) is a heterogeneous malignancy with high mortality and dismal prognosis, and an urgent clinical need for new therapies. Knowledge of the CCA epigenome is largely limited to aberrant DNA methylation. Dysregulation of enhancer activities has been identified to affect carcinogenesis and leveraged for new therapies but...
Alternative Titles
Full title
Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholangiocarcinoma of different etiologies
Authors, Artists and Contributors
Author / Creator
Yong, Chern Han
Heng, Hong Lee
Chan, Jason Yongsheng
Lau, Mai Chan
Chen, Jianfeng
Lee, Jing Yi
Lim, Abner Herbert
Li, Zhimei
Guan, Peiyong
Chu, Pek Lim
Boot, Arnoud
Ng, Sheng Rong
Yao, Xiaosai
Wee, Felicia Yu Ting
Lim, Jeffrey Chun Tatt
Liu, Wei
Wang, Peili
Xiao, Rong
Zeng, Xian
Sun, Yichen
Koh, Joanna
Kwek, Xiu Yi
Ng, Cedric Chuan Young
Klanrit, Poramate
Zhang, Yaojun
Lai, Jiaming
Tai, David Wai Meng
Pairojkul, Chawalit
Dima, Simona
Popescu, Irinel
Hsieh, Sen-Yung
Yu, Ming-Chin
Yeong, Joe
Kongpetch, Sarinya
Jusakul, Apinya
Loilome, Watcharin
Tan, Patrick
Tan, Jing
Teh, Bin Tean
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2898313694
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2898313694
Other Identifiers
ISSN
0017-5749,1468-3288
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2023-330483
