Targeting hypoxia-inducible factors: therapeutic opportunities and challenges
Targeting hypoxia-inducible factors: therapeutic opportunities and challenges
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Hypoxia-inducible factors (HIFs) are highly conserved transcription factors that are crucial for adaptation of metazoans to limited oxygen availability. Recently, HIF activation and inhibition have emerged as therapeutic targets in various human diseases. Pharmacologically desirable effects of HIF activation include erythropoiesis stimulation, cell...
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Full title
Targeting hypoxia-inducible factors: therapeutic opportunities and challenges
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TN_cdi_proquest_miscellaneous_2904574624
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2904574624
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ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/s41573-023-00848-6
