Tonic ErbB signaling underlies TGFβ-induced activation of ERK and is required for lens cell epitheli...
Tonic ErbB signaling underlies TGFβ-induced activation of ERK and is required for lens cell epithelial to myofibroblast transition
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Publisher
United States
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Language
English
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United States
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Contents
Fibrosis is a major, but incompletely understood, component of many diseases. The most common vision-disrupting complication of cataract surgery involves differentiation of residual lens cells into myofibroblasts. In serum-free primary cultures of lens epithelial cells (DCDMLs), inhibitors of either ERK or of ErbB signaling prevent TGFβ from upregu...
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Full title
Tonic ErbB signaling underlies TGFβ-induced activation of ERK and is required for lens cell epithelial to myofibroblast transition
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TN_cdi_proquest_miscellaneous_2910190025
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2910190025
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ISSN
1059-1524
E-ISSN
1939-4586
DOI
10.1091/mbc.E23-07-0294
