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Small-Molecule-Directed Endogenous Regeneration of Visual Function in a Mammalian Retinal Degenerati...

Small-Molecule-Directed Endogenous Regeneration of Visual Function in a Mammalian Retinal Degenerati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2925000455

Small-Molecule-Directed Endogenous Regeneration of Visual Function in a Mammalian Retinal Degeneration Model

About this item

Full title

Small-Molecule-Directed Endogenous Regeneration of Visual Function in a Mammalian Retinal Degeneration Model

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2024-02, Vol.25 (3), p.1521

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Degenerative retinal diseases associated with photoreceptor loss are a leading cause of visual impairment worldwide, with limited treatment options. Phenotypic profiling coupled with medicinal chemistry were used to develop a small molecule with proliferative effects on retinal stem/progenitor cells, as assessed in vitro in a neurosphere assay and...

Alternative Titles

Full title

Small-Molecule-Directed Endogenous Regeneration of Visual Function in a Mammalian Retinal Degeneration Model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2925000455

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2925000455

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms25031521

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