Biomarker-directed targeted therapy plus durvalumab in advanced non-small-cell lung cancer: a phase...
Biomarker-directed targeted therapy plus durvalumab in advanced non-small-cell lung cancer: a phase 2 umbrella trial
About this item
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Author / Creator
Besse, Benjamin , Pons-Tostivint, Elvire , Park, Keunchil , Hartl, Sylvia , Forde, Patrick M. , Hochmair, Maximilian J. , Awad, Mark M. , Thomas, Michael , Goss, Glenwood , Wheatley-Price, Paul , Shepherd, Frances A. , Florescu, Marie , Cheema, Parneet , Chu, Quincy S. C. , Kim, Sang-We , Morgensztern, Daniel , Johnson, Melissa L. , Cousin, Sophie , Kim, Dong-Wan , Moskovitz, Mor T. , Vicente, David , Aronson, Boaz , Hobson, Rosalind , Ambrose, Helen J. , Khosla, Sajan , Reddy, Avinash , Russell, Deanna L. , Keddar, Mohamed Reda , Conway, James P. , Barrett, J. Carl , Dean, Emma , Kumar, Rakesh , Dressman, Marlene , Jewsbury, Philip J. , Iyer, Sonia , Barry, Simon T. , Cosaert, Jan and Heymach, John V.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
For patients with non-small-cell lung cancer (NSCLC) tumors without currently targetable molecular alterations, standard-of-care treatment is immunotherapy with anti-PD-(L)1 checkpoint inhibitors, alone or with platinum-doublet therapy. However, not all patients derive durable benefit and resistance to immune checkpoint blockade is common. Understa...
Alternative Titles
Full title
Biomarker-directed targeted therapy plus durvalumab in advanced non-small-cell lung cancer: a phase 2 umbrella trial
Authors, Artists and Contributors
Author / Creator
Pons-Tostivint, Elvire
Park, Keunchil
Hartl, Sylvia
Forde, Patrick M.
Hochmair, Maximilian J.
Awad, Mark M.
Thomas, Michael
Goss, Glenwood
Wheatley-Price, Paul
Shepherd, Frances A.
Florescu, Marie
Cheema, Parneet
Chu, Quincy S. C.
Kim, Sang-We
Morgensztern, Daniel
Johnson, Melissa L.
Cousin, Sophie
Kim, Dong-Wan
Moskovitz, Mor T.
Vicente, David
Aronson, Boaz
Hobson, Rosalind
Ambrose, Helen J.
Khosla, Sajan
Reddy, Avinash
Russell, Deanna L.
Keddar, Mohamed Reda
Conway, James P.
Barrett, J. Carl
Dean, Emma
Kumar, Rakesh
Dressman, Marlene
Jewsbury, Philip J.
Iyer, Sonia
Barry, Simon T.
Cosaert, Jan
Heymach, John V.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2926519398
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2926519398
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-024-02808-y