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Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma
Author / Creator:Kim, Nayoung ; Kim, Hong Kwan ; Lee, Kyungjong ; Hong, Yourae ; Cho, Jong Ho ; Choi, Jung Won ; Lee, Jung-Il ; Suh, Yeon-Lim ; Ku, Bo Mi ; Eum, Hye Hyeon ; Choi, Soyean ; Choi, Yoon-La ; Joung, Je-Gun ; Park, Woong-Yang ; Jung, Hyun Ae ; Sun, Jong-Mu ; Lee, Se-Hoon ; Ahn, Jin Seok ; Park, Keunchil ; Ahn, Myung-Ju ; Lee, Hae-Ock
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-05, Vol.11 (1), p.2285-2285, Article 2285
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DNA methylation loss promotes immune evasion of tumours with high mutation and copy number load
Author / Creator:Jung, Hyunchul ; Kim, Hong Sook ; Kim, Jeong Yeon ; Sun, Jong-Mu ; Ahn, Jin Seok ; Ahn, Myung-Ju ; Park, Keunchil ; Esteller, Manel ; Lee, Se-Hoon ; Choi, Jung Kyoon
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-09, Vol.10 (1), p.4278-12, Article 4278
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Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours
Author / Creator:Hong, David S. ; Kang, Yoon-Koo ; Borad, Mitesh ; Sachdev, Jasgit ; Ejadi, Samuel ; Lim, Ho Yeong ; Brenner, Andrew J. ; Park, Keunchil ; Lee, Jae-Lyun ; Kim, Tae-You ; Shin, Sangjoon ; Becerra, Carlos R. ; Falchook, Gerald ; Stoudemire, Jay ; Martin, Desiree ; Kelnar, Kevin ; Peltier, Heidi ; Bonato, Vinicius ; Bader, Andreas G. ; Smith, Susan ; Kim, Sinil ; O’Neill, Vincent ; Beg, Muhammad S.
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2020-05, Vol.122 (11), p.1630-1637
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Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial
Author / Creator:Fehrenbacher, Louis, Dr ; Spira, Alexander, MD ; Ballinger, Marcus, PhD ; Kowanetz, Marcin, PhD ; Vansteenkiste, Johan, Prof ; Mazieres, Julien, Prof ; Park, Keunchil, Prof ; Smith, David, MD ; Artal-Cortes, Angel, MD ; Lewanski, Conrad, MD ; Braiteh, Fadi, MD ; Waterkamp, Daniel, MD ; He, Pei, PhD ; Zou, Wei, PhD ; Chen, Daniel S, MD ; Yi, Jing, PhD ; Sandler, Alan, MD ; Rittmeyer, Achim, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2016-04, Vol.387 (10030), p.1837-1846
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Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial
Author / Creator:Rittmeyer, Achim, MD ; Barlesi, Fabrice, PhD ; Waterkamp, Daniel, MD ; Park, Keunchil, MD ; Ciardiello, Fortunato, MD ; von Pawel, Joachim, MD ; Gadgeel, Shirish M, MD ; Hida, Toyoaki, PhD ; Kowalski, Dariusz M, PhD ; Dols, Manuel Cobo, MD ; Cortinovis, Diego L, PhD ; Leach, Joseph, MD ; Polikoff, Jonathan, MD ; Barrios, Carlos, MD ; Kabbinavar, Fairooz, MD ; Frontera, Osvaldo Arén, MD ; De Marinis, Filippo, MD ; Turna, Hande, MD ; Lee, Jong-Seok, MD ; Ballinger, Marcus, PhD ; Kowanetz, Marcin, PhD ; He, Pei, PhD ; Chen, Daniel S, MD ; Sandler, Alan, MD ; Gandara, David R, Dr
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2017-01, Vol.389 (10066), p.255-265
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Predicting clinical benefit of immunotherapy by antigenic or functional mutations affecting tumour immunogenicity
Author / Creator:Kim, Kwoneel ; Kim, Hong Sook ; Kim, Jeong Yeon ; Jung, Hyunchul ; Sun, Jong-Mu ; Ahn, Jin Seok ; Ahn, Myung-Ju ; Park, Keunchil ; Lee, Se-Hoon ; Choi, Jung Kyoon
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-02, Vol.11 (1), p.951-951, Article 951
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Avelumab versus docetaxel in patients with platinum-treated advanced non-small-cell lung cancer (JAVELIN Lung 200): an open-label, randomised, phase 3 study
Author / Creator:Barlesi, Fabrice, Prof ; Vansteenkiste, Johan, Prof ; Spigel, David, MD ; Ishii, Hidenobu, MD ; Garassino, Marina, MD ; de Marinis, Filippo, MD ; Özgüroğlu, Mustafa, Prof ; Szczesna, Aleksandra, MD ; Polychronis, Andreas, PhD ; Uslu, Ruchan, MD ; Krzakowski, Maciej, Prof ; Lee, Jong-Seok, Prof ; Calabrò, Luana, MD ; Arén Frontera, Osvaldo, MD ; Ellers-Lenz, Barbara, MS ; Bajars, Marcis, MD ; Ruisi, Mary, MD ; Park, Keunchil, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2018-11, Vol.19 (11), p.1468-1479
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Afatinib versus gefitinib as first-line treatment of patients with EGFR mutation-positive non-small-cell lung cancer (LUX-Lung 7): a phase 2B, open-label, randomised controlled trial
Author / Creator:Park, Keunchil, Prof ; Tan, Eng-Huat, MD ; O'Byrne, Ken, Prof ; Zhang, Li, Prof ; Boyer, Michael, Prof ; Mok, Tony, Prof ; Hirsh, Vera, Prof ; Yang, James Chih-Hsin, Prof ; Lee, Ki Hyeong, MD ; Lu, Shun, Prof ; Shi, Yuankai, MD ; Kim, Sang-We, MD ; Laskin, Janessa, MD ; Kim, Dong-Wan, Prof ; Arvis, Catherine Dubos, MD ; Kölbeck, Karl, MD ; Laurie, Scott A, MD ; Tsai, Chun-Ming, Prof ; Shahidi, Mehdi, MD ; Kim, Miyoung, MD ; Massey, Dan, PhD ; Zazulina, Victoria, MD ; Paz-Ares, Luis, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-05, Vol.17 (5), p.577-589
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Regulatory (FoxP3+) T cells and TGF-β predict the response to anti-PD-1 immunotherapy in patients with non-small cell lung cancer
Author / Creator:Koh, Jiae ; Hur, Joon Young ; Lee, Kyoung Young ; Kim, Mi Soon ; Heo, Jae Yeong ; Ku, Bo Mi ; Sun, Jong-Mu ; Lee, Se-Hoon ; Ahn, Jin Seok ; Park, Keunchil ; Ahn, Myung-Ju
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-11, Vol.10 (1), p.18994, Article 18994
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Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, do...
Author / Creator:Garon, Edward B, Dr ; Ciuleanu, Tudor-Eliade, Prof ; Arrieta, Oscar, MD ; Prabhash, Kumar, Prof ; Syrigos, Konstantinos N, Prof ; Goksel, Tuncay, Prof ; Park, Keunchil, Prof ; Gorbunova, Vera, MD ; Kowalyszyn, Ruben Dario, MD ; Pikiel, Joanna, MD ; Czyzewicz, Grzegorz, MD ; Orlov, Sergey V, Prof ; Lewanski, Conrad R, MD ; Thomas, Michael, Prof ; Bidoli, Paolo, MD ; Dakhil, Shaker, MD ; Gans, Steven, MD ; Kim, Joo-Hang, Prof ; Grigorescu, Alexandru, Prof ; Karaseva, Nina, MD ; Reck, Martin, MD ; Cappuzzo, Federico, MD ; Alexandris, Ekaterine, MS ; Sashegyi, Andreas, PhD ; Yurasov, Sergey, MD ; Pérol, Maurice, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2014-08, Vol.384 (9944), p.665-673
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Entrectinib resistance mechanisms in ROS1-rearranged non-small cell lung cancer
Author / Creator:Ku, Bo Mi ; Bae, Yeon Hee ; Lee, Kyoung Young ; Sun, Jong-Mu ; Lee, Se-Hoon ; Ahn, Jin Seok ; Park, Keunchil ; Ahn, Myung-Ju
Publisher:New York: Springer US
Journal title:Investigational new drugs, 2020-04, Vol.38 (2), p.360-368
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Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/...
Author / Creator:Miller, Vincent A, Prof ; Hirsh, Vera, MD ; Cadranel, Jacques, Prof ; Chen, Yuh-Min, MD ; Park, Keunchil, Prof ; Kim, Sang-We, Prof ; Zhou, Caicun, Prof ; Su, Wu-Chou, Prof ; Wang, Mengzhao, Prof ; Sun, Yan, Prof ; Heo, Dae Seog, Prof ; Crino, Lucio, Prof ; Tan, Eng-Huat, MD ; Chao, Tsu-Yi, Prof ; Shahidi, Mehdi, MD ; Cong, Xiuyu Julie, PhD ; Lorence, Robert M, MD ; Yang, James Chih-Hsin, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2012-05, Vol.13 (5), p.528-538
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Necitumumab plus gemcitabine and cisplatin versus gemcitabine and cisplatin alone as first-line therapy in patients with stage IV squamous non-small-cell lung cancer (SQUIRE): an open-label, randomise...
Author / Creator:Thatcher, Nick, Prof ; Hirsch, Fred R, Prof ; Luft, Alexander V, MD ; Szczesna, Aleksandra, MD ; Ciuleanu, Tudor E, Prof ; Dediu, Mircea, MD ; Ramlau, Rodryg, Prof ; Galiulin, Rinat K, MD ; Bálint, Beatrix, MD ; Losonczy, György, Prof ; Kazarnowicz, Andrzej, MD ; Park, Keunchil, MD ; Schumann, Christian, Prof ; Reck, Martin, MD ; Depenbrock, Henrik, MD ; Nanda, Shivani, MS ; Kruljac-Letunic, Anamarija, PhD ; Kurek, Raffael, MD ; Paz-Ares, Luis, MD ; Socinski, Mark A, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-07, Vol.16 (7), p.763-774
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Six versus fewer planned cycles of first-line platinum-based chemotherapy for non-small-cell lung cancer: a systematic review and meta-analysis of individual patient data
Author / Creator:Rossi, Antonio, Dr ; Chiodini, Paolo, PhD ; Sun, Jong-Mu, MD ; O'Brien, Mary E R, MD ; von Plessen, Christian, MD ; Barata, Fernando, MD ; Park, Keunchil, Prof ; Popat, Sanjay, FRCP ; Bergman, Bengt, MD ; Parente, Barbara, MD ; Gallo, Ciro, Prof ; Gridelli, Cesare, MD ; Perrone, Francesco, MD ; Di Maio, Massimo, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2014-10, Vol.15 (11), p.1254-1262
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Integrative genomic analysis of salivary duct carcinoma
Author / Creator:Kim, Youngwook ; Song, Sanghoon ; Lee, Miran ; Swatloski, Teresa ; Kang, Joon Ho ; Ko, Young-Hyeh ; Park, Woong-Yang ; Jeong, Han-Sin ; Park, Keunchil
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-09, Vol.10 (1), p.14995-14995, Article 14995
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Prevalence and detection of low-allele-fraction variants in clinical cancer samples
Author / Creator:Shin, Hyun-Tae ; Choi, Yoon-La ; Yun, Jae Won ; Kim, Nayoung K. D. ; Kim, Sook-Young ; Jeon, Hyo Jeong ; Nam, Jae-Yong ; Lee, Chung ; Ryu, Daeun ; Kim, Sang Cheol ; Park, Kyunghee ; Lee, Eunjin ; Bae, Joon Seol ; Son, Dae Soon ; Joung, Je-Gun ; Lee, Jeeyun ; Kim, Seung Tae ; Ahn, Myung-Ju ; Lee, Se-Hoon ; Ahn, Jin Seok ; Lee, Woo Yong ; Oh, Bo Young ; Park, Yeon Hee ; Lee, Jeong Eon ; Lee, Kwang Hyuk ; Kim, Hee Cheol ; Kim, Kyoung-Mee ; Im, Young-Hyuck ; Park, Keunchil ; Park, Peter J. ; Park, Woong-Yang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-11, Vol.8 (1), p.1377-10, Article 1377
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EGFR expression as a predictor of survival for first-line chemotherapy plus cetuximab in patients with advanced non-small-cell lung cancer: analysis of data from the phase 3 FLEX study
Author / Creator:Pirker, Robert, Prof ; Pereira, Jose R, MD ; von Pawel, Joachim, MD ; Krzakowski, Maciej, Prof ; Ramlau, Rodryg, MD ; Park, Keunchil, Prof ; de Marinis, Filippo, MD ; Eberhardt, Wilfried EE, MD ; Paz-Ares, Luis, MD ; Störkel, Stephan, Prof ; Schumacher, Karl-Maria, MD ; von Heydebreck, Anja, PhD ; Celik, Ilhan, Prof ; O'Byrne, Kenneth J, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2012, Vol.13 (1), p.33-42
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Ramucirumab or placebo plus erlotinib in EGFR‐mutated, metastatic non‐small‐cell lung cancer: East Asian subset of RELAY
Author / Creator:Nishio, Makoto ; Seto, Takashi ; Reck, Martin ; Garon, Edward B. ; Chiu, Chao‐Hua ; Yoh, Kiyotaka ; Imamura, Fumio ; Park, Keunchil ; Shih, Jin‐Yuan ; Visseren‐Grul, Carla ; Frimodt‐Moller, Bente ; Zimmermann, Annamaria ; Homma, Gosuke ; Enatsu, Sotaro ; Nakagawa, Kazuhiko
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2020-12, Vol.111 (12), p.4510-4525
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Tolerability and efficacy of durvalumab, either as monotherapy or in combination with tremelimumab, in patients from Asia with advanced biliary tract, esophageal, or head‐and‐neck cancer
Author / Creator:Doki, Yuichiro ; Ueno, Makoto ; Hsu, Chih‐Hung ; Oh, Do‐Youn ; Park, Keunchil ; Yamamoto, Noboru ; Ioka, Tatsuya ; Hara, Hiroki ; Hayama, Manabu ; Nii, Masahiro ; Komuro, Keiko ; Sugimoto, Mariko ; Tahara, Makoto
Publisher:United States: John Wiley & Sons, Inc
Journal title:Cancer medicine (Malden, MA), 2022-07, Vol.11 (13), p.2550-2560
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Identification of Driving ALK Fusion Genes and Genomic Landscape of Medullary Thyroid Cancer
Author / Creator:Ji, Jun Ho ; Oh, Young Lyun ; Hong, Mineui ; Yun, Jae Won ; Lee, Hyun-Woo ; Kim, DeokGeun ; Ji, Yongick ; Kim, Duk-Hwan ; Park, Woong-Yang ; Shin, Hyun-Tae ; Kim, Kyoung-Mee ; Ahn, Myung-Ju ; Park, Keunchil ; Sun, Jong-Mu
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2015-08, Vol.11 (8), p.e1005467-e1005467
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Showing 1 to 20 of 153 results

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Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma

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DNA methylation loss promotes immune evasion of tumours with high mutation and copy number load

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Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours

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Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial

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Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial

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Predicting clinical benefit of immunotherapy by antigenic or functional mutations affecting tumour immunogenicity

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Avelumab versus docetaxel in patients with platinum-treated advanced non-small-cell lung cancer (JAVELIN Lung 200): an open-label, randomised, phase 3 study

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Afatinib versus gefitinib as first-line treatment of patients with EGFR mutation-positive non-small-cell lung cancer (LUX-Lung 7): a phase 2B, open-label, randomised controlled trial

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Regulatory (FoxP3+) T cells and TGF-β predict the response to anti-PD-1 immunotherapy in patients with non-small cell lung cancer

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Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, do...

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Entrectinib resistance mechanisms in ROS1-rearranged non-small cell lung cancer

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Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/...

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Necitumumab plus gemcitabine and cisplatin versus gemcitabine and cisplatin alone as first-line therapy in patients with stage IV squamous non-small-cell lung cancer (SQUIRE): an open-label, randomise...

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Six versus fewer planned cycles of first-line platinum-based chemotherapy for non-small-cell lung cancer: a systematic review and meta-analysis of individual patient data

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Integrative genomic analysis of salivary duct carcinoma

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Prevalence and detection of low-allele-fraction variants in clinical cancer samples

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EGFR expression as a predictor of survival for first-line chemotherapy plus cetuximab in patients with advanced non-small-cell lung cancer: analysis of data from the phase 3 FLEX study

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Ramucirumab or placebo plus erlotinib in EGFR‐mutated, metastatic non‐small‐cell lung cancer: East Asian subset of RELAY

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Tolerability and efficacy of durvalumab, either as monotherapy or in combination with tremelimumab, in patients from Asia with advanced biliary tract, esophageal, or head‐and‐neck cancer

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Identification of Driving ALK Fusion Genes and Genomic Landscape of Medullary Thyroid Cancer

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