Early consequences of the phospholamban mutation PLN‐R14del+/− in a transgenic mouse model
Early consequences of the phospholamban mutation PLN‐R14del+/− in a transgenic mouse model
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England: Wiley Subscription Services, Inc
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English
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England: Wiley Subscription Services, Inc
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The heterozygous phospholamban (PLN) mutation R14del (PLN R14del+/−) is associated with a severe arrhythmogenic cardiomyopathy (ACM) developing in the adult. “Superinhibition” of SERCA2a by PLN R14del is widely assumed to underlie the pathogenesis, but alternative mechanisms such abnormal energy metabolism have also been reported. This work...
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Early consequences of the phospholamban mutation PLN‐R14del+/− in a transgenic mouse model
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TN_cdi_proquest_miscellaneous_2929030564
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2929030564
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ISSN
1748-1708,1748-1716
E-ISSN
1748-1716
DOI
10.1111/apha.14082
