Methylprednisolone Modulates the Tfr/Tfh ratio in EAE-Induced Neuroinflammation through the PI3K/AKT...
Methylprednisolone Modulates the Tfr/Tfh ratio in EAE-Induced Neuroinflammation through the PI3K/AKT/FoxO1 and PI3K/AKT/mTOR Signalling Pathways
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Author / Creator
Wu, Nan , Zhao, Yun , Xiao, Minjun , Liu, Hui , Chen, Hongliang , Liu, Bin , Wang, Xuezhen and Fan, Xueli
Publisher
United States
Journal title
Language
English
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Publisher
United States
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Contents
Methylprednisolone (MP) is a potent glucocorticoid that can effectively inhibit immune system inflammation and brain tissue damage in Multiple sclerosis (MS) patients. T follicular helper (Tfh) cells are a subpopulation of activated CD4 + T cells, while T follicular regulatory (Tfr) cells, a novel subset of Treg cells, possess specialized abilities...
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Full title
Methylprednisolone Modulates the Tfr/Tfh ratio in EAE-Induced Neuroinflammation through the PI3K/AKT/FoxO1 and PI3K/AKT/mTOR Signalling Pathways
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_3077189143
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3077189143
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ISSN
0360-3997,1573-2576
E-ISSN
1573-2576
DOI
10.1007/s10753-024-02099-y