Discovery of NFκB2-Coordinated Dual Regulation of Mitochondrial and Nuclear Genomes Leads to an Effe...
Discovery of NFκB2-Coordinated Dual Regulation of Mitochondrial and Nuclear Genomes Leads to an Effective Therapy for Acute Myeloid Leukemia
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Acute myeloid leukemia (AML) has a poor survival rate for both pediatric and adult patients due to its frequent relapse. To elucidate the bioenergetic principle underlying AML relapse, we investigated the transcriptional regulation of mitochondrial-nuclear dual genomes responsible for metabolic plasticity in treatment-resistant blasts. Both the gai...
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Discovery of NFκB2-Coordinated Dual Regulation of Mitochondrial and Nuclear Genomes Leads to an Effective Therapy for Acute Myeloid Leukemia
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TN_cdi_proquest_miscellaneous_3091287221
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3091287221
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms25158532
