Effect of Everolimus on Prognosis of Neurofibromatosis Type 1 Lesions: A Systematic Review and Meta...
Effect of Everolimus on Prognosis of Neurofibromatosis Type 1 Lesions: A Systematic Review and Meta Analysis
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United States: Elsevier Inc
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English
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United States: Elsevier Inc
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Highlights•Neurofibromatosis Type 1 (NF-1) is a genetic disorder caused by NF1 gene mutations, leading to neurofibromas. •Explored everolimus, an mTOR inhibitor, for its effect on NF-1 lesion size via meta-analysis. •Four phase II trials with 83 patients showed no significant effect of oral everolimus on lesion size reduction. •Safety discrepancies...
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Effect of Everolimus on Prognosis of Neurofibromatosis Type 1 Lesions: A Systematic Review and Meta Analysis
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TN_cdi_proquest_miscellaneous_3101796208
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3101796208
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ISSN
0149-2918,1879-114X
E-ISSN
1879-114X
DOI
10.1016/j.clinthera.2024.08.009
