Role of Non-Binding T63 Alteration in IL-18 Binding
Role of Non-Binding T63 Alteration in IL-18 Binding
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Engineered interleukin-18 (IL-18) has attracted interest as a cytokine-based treatment. However, knowledge-based mutagenesis of IL-18 has been reported for only a few regions of the protein structures, including binding sites I and II. When coupled with the binding region mutant (E6K), the non-binding residue of IL-18, Thr63 (T63), has been shown t...
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Full title
Role of Non-Binding T63 Alteration in IL-18 Binding
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TN_cdi_proquest_miscellaneous_3146915830
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3146915830
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms252312992
