Basic Science and Pathogenesis
Basic Science and Pathogenesis
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Publisher
United States
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Language
English
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United States
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Contents
Dysregulation of endolysosomal trafficking is a major pathogenic mechanism in Alzheimer's disease (AD). From the family of AD-linked endosomal pathway genes, SORL1 stands out as one of the highest risk factors. SORL1 encodes an endocytic sorting receptor that mediates endosomal trafficking and processing of key AD-associated molecules, including pa...
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Basic Science and Pathogenesis
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TN_cdi_proquest_miscellaneous_3151210811
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3151210811
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ISSN
1552-5279
E-ISSN
1552-5279
DOI
10.1002/alz.092619