Basic Science and Pathogenesis
Basic Science and Pathogenesis
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United States
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Language
English
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United States
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Contents
The classic mode of STING activation is through binding the cyclic dinucleotide 2'3'-cyclic GMP-AMP (cGAMP), produced by the DNA sensor cyclic GMP-AMP synthase (cGAS), which is important for the innate immune response to microbial infection and autoimmune disease. Modes of STING activation that are independent of cGAS are much less well understood....
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Basic Science and Pathogenesis
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TN_cdi_proquest_miscellaneous_3151212500
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3151212500
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ISSN
1552-5279
E-ISSN
1552-5279
DOI
10.1002/alz.084589