The neurite outgrowth inhibitor Nogo A is involved in autoimmune-mediated demyelination
The neurite outgrowth inhibitor Nogo A is involved in autoimmune-mediated demyelination
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Inhibitors associated with CNS myelin are thought to be important in the failure of axons to regenerate after spinal cord injury and in other neurodegenerative disorders. Here we show that targeting the CNS-specific inhibitor of neurite outgrowth Nogo A by active immunization blunts clinical signs, demyelination and axonal damage associated with ex...
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Full title
The neurite outgrowth inhibitor Nogo A is involved in autoimmune-mediated demyelination
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TN_cdi_proquest_miscellaneous_66658783
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66658783
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn1261
