The endoplasmic reticulum stress response in immunity and autoimmunity
The endoplasmic reticulum stress response in immunity and autoimmunity
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Key Points
Misfolded proteins cause intracellular stress, which induces the unfolded-protein response (UPR). The UPR is a three-pronged signalling pathway that induces genes which cause cells to acquire a secretory phenotype.
The branches of the UPR are mediated by the three endoplasmic reticulum (ER)-resident proteins: inositol-requiring 1 t...
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Full title
The endoplasmic reticulum stress response in immunity and autoimmunity
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TN_cdi_proquest_miscellaneous_66662738
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66662738
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ISSN
1474-1733
E-ISSN
1474-1741
DOI
10.1038/nri2359
