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Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast...

Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66796830

Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis

About this item

Full title

Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis

Publisher

United States

Journal title

The Journal of clinical investigation, 2009-01, Vol.119 (1), p.213-224

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

Pulmonary fibrosis, in particular idiopathic pulmonary fibrosis (IPF), results from aberrant wound healing and scarification. One population of fibroblasts involved in the fibrotic process is thought to originate from lung epithelial cells via epithelial-mesenchymal transition (EMT). Indeed, alveolar epithelial cells (AECs) undergo EMT in vivo duri...

Alternative Titles

Full title

Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_66796830

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66796830

Other Identifiers

ISSN

0021-9738

DOI

10.1172/JCI36940

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