Hypoxia-inducible factor–dependent induction of netrin-1 dampens inflammation caused by hypoxia
Hypoxia-inducible factor–dependent induction of netrin-1 dampens inflammation caused by hypoxia
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Hypoxia incites inflammation, particularly at mucosal surfaces. Eltzschig and colleagues show that hypoxia also suppresses inflammation by inducing expression of the neuronal guidance molecule netrin-1, which inhibits the transepithelial migration of neutrophils.
The neuronal guidance molecule netrin-1 is linked to the coordination of inflammato...
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Hypoxia-inducible factor–dependent induction of netrin-1 dampens inflammation caused by hypoxia
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TN_cdi_proquest_miscellaneous_66824340
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66824340
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.1683
