Molecular-Genetic PET Imaging Using an HSV1-tk Mutant Reporter Gene with Enhanced Specificity to Acy...
Molecular-Genetic PET Imaging Using an HSV1-tk Mutant Reporter Gene with Enhanced Specificity to Acycloguanosine Nucleoside Analogs
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Publisher
United States: Soc Nuclear Med
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Language
English
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Publisher
United States: Soc Nuclear Med
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Contents
Imaging 2 different molecular-genetic events in a single subject by PET is essential in a variety of in vivo applications. Using herpes simplex virus-1 thymidine kinase (HSV1-tk) mutants with narrower substrate specificities in combination with wild-type HSV1-tk (wtHSV1-tk) would enable differential imaging with corresponding radiotracers, namely 2...
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Full title
Molecular-Genetic PET Imaging Using an HSV1-tk Mutant Reporter Gene with Enhanced Specificity to Acycloguanosine Nucleoside Analogs
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TN_cdi_proquest_miscellaneous_66989627
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66989627
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ISSN
0161-5505
E-ISSN
1535-5667,2159-662X
DOI
10.2967/jnumed.108.058735
