p53 represses c-Myc through induction of the tumor suppressor miR-145
p53 represses c-Myc through induction of the tumor suppressor miR-145
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The tumor suppressor p53 negatively regulates a number of genes, including the proto-oncogene c-Myc, in addition to activating many other genes. One mechanism of the p53-mediated c-Myc repression may involve transcriptional regulation. However, it is not clear whether microRNAs (miRNAs) play a role in the p53-mediated posttranscriptional regulation...
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Full title
p53 represses c-Myc through induction of the tumor suppressor miR-145
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TN_cdi_proquest_miscellaneous_66990886
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66990886
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0808042106
