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6-Phosphogluconate Dehydrogenase: A Target for Drugs in African Trypanosomes

6-Phosphogluconate Dehydrogenase: A Target for Drugs in African Trypanosomes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67073799

6-Phosphogluconate Dehydrogenase: A Target for Drugs in African Trypanosomes

About this item

Full title

6-Phosphogluconate Dehydrogenase: A Target for Drugs in African Trypanosomes

Publisher

Schiphol: Bentham Science Publishers Ltd

Journal title

Current medicinal chemistry, 2004-10, Vol.11 (19), p.2639-2650

Language

English

Formats

Publication information

Publisher

Schiphol: Bentham Science Publishers Ltd

More information

Scope and Contents

Contents

New drugs are urgently required for Human African Trypanosomiasis (sleeping sickness), a disease which has re-emerged as a major health threat in Sub-Saharan Africa. The third enzyme of the pentose phosphate pathway, 6-phosphogluconate dehydrogenase, has been shown to be a good target for drugs. The enzyme is essential to the trypanosomes that caus...

Alternative Titles

Full title

6-Phosphogluconate Dehydrogenase: A Target for Drugs in African Trypanosomes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67073799

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67073799

Other Identifiers

ISSN

0929-8673

E-ISSN

1875-533X

DOI

10.2174/0929867043364441

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