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Truncated tau at D421 is associated with neurodegeneration and tangle formation in the brain of Alzh...

Truncated tau at D421 is associated with neurodegeneration and tangle formation in the brain of Alzh...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67240608

Truncated tau at D421 is associated with neurodegeneration and tangle formation in the brain of Alzheimer transgenic models

About this item

Full title

Truncated tau at D421 is associated with neurodegeneration and tangle formation in the brain of Alzheimer transgenic models

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Acta neuropathologica, 2009-06, Vol.117 (6), p.687-697

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

In addition to tau hyperphosphorylation, tau truncation is also detected in Alzheimer’s disease (AD) patients. In the brain of AD transgenic mouse models, the pathological details of truncated tau are not well characterized. In this study, we analyzed spatial relationships among tau truncation, tau phosphorylation and neurodegeneration or tangle fo...

Alternative Titles

Full title

Truncated tau at D421 is associated with neurodegeneration and tangle formation in the brain of Alzheimer transgenic models

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67240608

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67240608

Other Identifiers

ISSN

0001-6322

E-ISSN

1432-0533

DOI

10.1007/s00401-009-0491-6

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