Crystal Structure of the Nuclear Export Receptor CRM1 in Complex with Snurportin1 and RanGTP
Crystal Structure of the Nuclear Export Receptor CRM1 in Complex with Snurportin1 and RanGTP
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Washington, DC: American Association for the Advancement of Science
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English
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Washington, DC: American Association for the Advancement of Science
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Contents
CRM1 mediates nuclear export of numerous unrelated cargoes, which may carry a short leucine-rich nuclear export signal or export signatures that include folded domains. How CRM1 recognizes such a variety of cargoes has been unknown up to this point. Here we present the crystal structure of the SPN1·CRM1·RanGTP export complex at 2.5 angstrom resolut...
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Full title
Crystal Structure of the Nuclear Export Receptor CRM1 in Complex with Snurportin1 and RanGTP
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TN_cdi_proquest_miscellaneous_67275496
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67275496
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1173388
