Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon–de...
Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon–dependent exhaustion
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Although type I interferons such as interferon-α are well known to protect against viral infection, they may have other physiological effects in the uninfected state. Taku Sato
et al
. now show that type I interferon signaling in hematopoietic stem cells promotes their proliferation and impairs their ability to reconstitute the hematopoietic...
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Full title
Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon–dependent exhaustion
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TN_cdi_proquest_miscellaneous_67335274
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67335274
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.1973
