Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans
Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
The tumor suppressor protein p53 plays an important role in maternal reproduction in mice through transcriptional regulation of leukemia inhibitory factor (LIF), a cytokine crucial for blastocyst implantation. To determine whether these observations could be extended to humans, a list of single-nucleotide polymorphisms (SNPs) in the p53 pathway tha...
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Full title
Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans
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TN_cdi_proquest_miscellaneous_67401370
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67401370
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0904280106