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Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67401370

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

About this item

Full title

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (24), p.9761-9766

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The tumor suppressor protein p53 plays an important role in maternal reproduction in mice through transcriptional regulation of leukemia inhibitory factor (LIF), a cytokine crucial for blastocyst implantation. To determine whether these observations could be extended to humans, a list of single-nucleotide polymorphisms (SNPs) in the p53 pathway tha...

Alternative Titles

Full title

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67401370

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67401370

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0904280106

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