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SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway

SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67529753

SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway

About this item

Full title

SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2009-08, Vol.12 (8), p.1011-1019

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

This study shows that, although AMPA-type glutamate receptors are trafficked to dendrites through the normal Golgi secretory pathway, NMDA receptors bypass the somatic Golgi apparatus and instead move from the endoplasmic reticulum in endoplasmic reticulum–like vesicles to Golgi 'outposts' located in the dendrites.
Synaptic plasticity is depende...

Alternative Titles

Full title

SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67529753

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67529753

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/nn.2362

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