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High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67567438

High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

About this item

Full title

High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Immunology, 2005-04, Vol.5 (4), p.331-342

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
High-mobility group box 1 protein (HMGB1) is a highly conserved nuclear protein that has a surprising extracellular role. Not only does it bind DNA, increasing access to transcription factors, but it also recruits cells across endothelial barriers and promotes the local production of tumour-necrosis factor (TNF), interleukin-6 (IL-6)...

Alternative Titles

Full title

High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67567438

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67567438

Other Identifiers

ISSN

1474-1733

E-ISSN

1474-1741

DOI

10.1038/nri1594

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