Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis
Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis
About this item
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Author / Creator
Cummings, Steven R , Martin, Javier San , McClung, Michael R , Siris, Ethel S , Eastell, Richard , Reid, Ian R , Delmas, Pierre , Zoog, Holly B , Austin, Matt , Wang, Andrea , Kutilek, Stepan , Adami, Silvano , Zanchetta, Jose , Libanati, Cesar , Siddhanti, Suresh , Christiansen, Claus and FREEDOM Trial
Publisher
Waltham, MA: Massachusetts Medical Society
Journal title
Language
English
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Publication information
Publisher
Waltham, MA: Massachusetts Medical Society
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More information
Scope and Contents
Contents
In this trial, women between the ages of 60 and 90 with low bone mineral density received twice-yearly subcutaneous injections of denosumab, a fully human monoclonal antibody against the receptor activator of nuclear factor-κB ligand, which inhibits the development and activity of osteoclasts, or placebo. Denosumab was associated with a reduced ris...
Alternative Titles
Full title
Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_67593606
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67593606
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa0809493
