Ascorbic acid inhibits antitumor activity of bortezomib in vivo
Ascorbic acid inhibits antitumor activity of bortezomib in vivo
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Author / Creator
Perrone, G , Hideshima, T , Ikeda, H , Okawa, Y , Calabrese, E , Gorgun, G , Santo, L , Cirstea, D , Raje, N , Chauhan, D , Baccarani, M , Cavo, M and Anderson, K C
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Earlier studies have shown that ascorbic acid (vitamin C) inhibits bortezomib-induced cytotoxicity against cancer cells
in vitro
. However, the clinical significance of vitamin C on bortezomib treatment is unclear. In this study, we examined whether daily oral intake of vitamin C inhibits antimultiple myeloma (MM) activities of bortezomib. Vi...
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Full title
Ascorbic acid inhibits antitumor activity of bortezomib in vivo
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TN_cdi_proquest_miscellaneous_67638857
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67638857
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ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2009.83