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ArticlesPeer ReviewedFull Text
Histone deacetylase 3 as a novel therapeutic target in multiple myeloma
Author / Creator:Minami, J ; Suzuki, R ; Mazitschek, R ; Gorgun, G ; Ghosh, B ; Cirstea, D ; Hu, Y ; Mimura, N ; Ohguchi, H ; Cottini, F ; Jakubikova, J ; Munshi, N C ; Haggarty, S J ; Richardson, P G ; Hideshima, T ; Anderson, K C
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2014-03, Vol.28 (3), p.680-689
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Class IIa HDAC inhibition enhances ER stress-mediated cell death in multiple myeloma
Author / Creator:Kikuchi, S ; Suzuki, R ; Ohguchi, H ; Yoshida, Y ; Lu, D ; Cottini, F ; Jakubikova, J ; Bianchi, G ; Harada, T ; Gorgun, G ; Tai, Y-T ; Richardson, P G ; Hideshima, T ; Anderson, K C
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2015-09, Vol.29 (9), p.1918-1927
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Ascorbic acid inhibits antitumor activity of bortezomib in vivo
Author / Creator:Perrone, G ; Hideshima, T ; Ikeda, H ; Okawa, Y ; Calabrese, E ; Gorgun, G ; Santo, L ; Cirstea, D ; Raje, N ; Chauhan, D ; Baccarani, M ; Cavo, M ; Anderson, K C
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2009-09, Vol.23 (9), p.1679-1686
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AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3β activation and RNA polymerase II inhibition
Author / Creator:Santo, L ; Vallet, S ; Hideshima, T ; Cirstea, D ; Ikeda, H ; Pozzi, S ; Patel, K ; Okawa, Y ; Gorgun, G ; Perrone, G ; Calabrese, E ; Yule, M ; Squires, M ; Ladetto, M ; Boccadoro, M ; Richardson, P G ; Munshi, N C ; Anderson, K C ; Raje, N
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2010-04, Vol.29 (16), p.2325-2336
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Small-molecule multi-targeted kinase inhibitor RGB-286638 triggers P53-dependent and -independent anti-multiple myeloma activity through inhibition of transcriptional CDKs
Author / Creator:Cirstea, D ; Hideshima, T ; Santo, L ; Eda, H ; Mishima, Y ; Nemani, N ; Hu, Y ; Mimura, N ; Cottini, F ; Gorgun, G ; Ohguchi, H ; Suzuki, R ; Loferer, H ; Munshi, N C ; Anderson, K C ; Raje, N
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2013-12, Vol.27 (12), p.2366-2375
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Rational combination treatment with histone deacetylase inhibitors and immunomodulatory drugs in multiple myeloma
Author / Creator:Hideshima, T ; Cottini, F ; Ohguchi, H ; Jakubikova, J ; Gorgun, G ; Mimura, N ; Tai, Y-T ; Munshi, N C ; Richardson, P G ; Anderson, K C
Publisher:London: Nature Publishing Group UK
Journal title:Blood cancer journal (New York), 2015-05, Vol.5 (5), p.e312-e312
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Anti-tumor activities of selective HSP90α/β inhibitor, TAS-116, in combination with bortezomib in multiple myeloma
Author / Creator:Suzuki, R ; Hideshima, T ; Mimura, N ; Minami, J ; Ohguchi, H ; Kikuchi, S ; Yoshida, Y ; Gorgun, G ; Cirstea, D ; Cottini, F ; Jakubikova, J ; Tai, Y-T ; Chauhan, D ; Richardson, P G ; Munshi, N C ; Utsugi, T ; Anderson, K C
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2015-02, Vol.29 (2), p.510-514
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Induction of differential apoptotic pathways in multiple myeloma cells by class-selective histone deacetylase inhibitors
Author / Creator:Hideshima, T ; Mazitschek, R ; Santo, L ; Mimura, N ; Gorgun, G ; Richardson, P G ; Raje, N ; Anderson, K C
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2014-02, Vol.28 (2), p.457-460
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A novel reduced intensity regimen for allogeneic hematopoietic stem cell transplantation associated with a reduced incidence of graft-versus-host disease
Author / Creator:Miller, K B ; Roberts, T F ; Chan, G ; Schenkein, D P ; Lawrence, D ; Sprague, K ; Gorgun, G ; Relias, V ; Grodman, H ; Mahajan, A ; Foss, F M
Publisher:Basingstoke: Nature Publishing Group
Journal title:Bone marrow transplantation (Basingstoke), 2004-05, Vol.33 (9), p.881-889
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Chronic lymphocytic leukemia cells induce changes in gene expression of CD4 and CD8 T cells
Author / Creator:Görgün, Güllü ; Holderried, Tobias A.W. ; Zahrieh, David ; Neuberg, Donna ; Gribben, John G.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2005-07, Vol.115 (7), p.1797-1805
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A novel rapid-onset high-penetrance plasmacytoma mouse model driven by deregulation of cMYC cooperating with KRAS12V in BALB/c mice
Author / Creator:Hu, Y ; Zheng, M ; Gali, R ; Tian, Z ; Topal Görgün, G ; Munshi, N C ; Mitsiades, C S ; Anderson, K C
Publisher:London: Nature Publishing Group UK
Journal title:Blood cancer journal (New York), 2013-11, Vol.3 (11), p.e156-e156
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ArticlesPeer ReviewedFull Text
Anti-tumor activities of selective HSP90[alpha]/[beta] inhibitor, TAS-116, in combination with bortezomib in multiple myeloma
Author / Creator:Ohguchi, H ; Minami, J ; Suzuki, R ; Mimura, N ; Kikuchi, S ; Yoshida, Y ; Hideshima, T
Publisher:London: Nature Publishing Group
Journal title:Leukemia, 2015-02, Vol.29 (2), p.510
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ArticlesPeer ReviewedFull Text
AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3b activation and RNA polymerase II inhibition
Author / Creator:Santo, L ; Vallet, S ; Hideshima, T ; Cirstea, D ; Ikeda, H ; Pozzi, S ; Patel, K ; Okawa, Y ; Gorgun, G ; Perrone, G ; Calabrese, E ; Yule, M ; Squires, M ; Ladetto, M ; Boccadoro, M ; Richardson, P G ; Munshi, N C ; Anderson, K C ; Raje, N
Journal title:Oncogene, 2010-04, Vol.29 (16), p.2325-2336
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ArticlesPeer ReviewedFull Text
AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3[beta] activation and RNA polymerase II inhibition
Author / Creator:Santo, L ; Vallet, S ; Hideshima, T ; Cirstea, D ; Ikeda, H ; Pozzi, S ; Patel, K ; Okawa, Y ; Gorgun, G ; Perrone, G ; Calabrese, E ; Yule, M ; Squires, M ; Ladetto, M ; Boccadoro, M ; Richardson, P G ; Munshi, N C ; Anderson, K C ; Raje, N
Publisher:New York: Nature Publishing Group
Journal title:Oncogene, 2010-04, Vol.29 (16), p.2325
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ArticlesPeer ReviewedFull Text
Extracorporeal photopheresis in chronic graft-versus-host disease
Author / Creator:Foss, FM ; Gorgun, G ; Miller, KB
Publisher:Basingstoke: Nature Publishing Group
Journal title:Bone marrow transplantation (Basingstoke), 2002-05, Vol.29 (9), p.719-725
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Extracorporeal photopheresis in chronic graft-versus-host disease: Mini-Review
Author / Creator:Foss, FM ; Gorgun, G ; Miller, KB
Publisher:London: Nature Publishing Group UK
Journal title:Bone marrow transplantation (Basingstoke), 2002-05, Vol.29 (9), p.719-725
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ArticlesPeer ReviewedFull Text
Extracorporeal photopheresis in chronic graft-versus-host disease
Author / Creator:Foss, F M ; Gorgun, G ; Miller, K B
Publisher:Nature Publishing Group
Journal title:Bone marrow transplantation (Basingstoke), 2002-05, Vol.29 (9), p.719
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A novel reduced intensity regimen for allogeneic hematopoietic stem cell transplantation associated with a reduced incidence of graft-versus-host disease: Reduced Intensity Conditioning Regimens
Author / Creator:Miller, K B ; Roberts, T F ; Chan, G ; Schenkein, D P ; Lawrence, D ; Sprague, K ; Gorgun, G ; Relias, V ; Grodman, H ; Mahajan, A ; Foss, F M
Publisher:London: Nature Publishing Group UK
Journal title:Bone marrow transplantation (Basingstoke), 2004-05, Vol.33 (9), p.881-889
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ArticlesPeer ReviewedFull Text
AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3beta activation and RNA polymerase II inhibition
Author / Creator:Santo, L ; Vallet, S ; Hideshima, T ; Cirstea, D ; Ikeda, H ; Pozzi, S ; Patel, K ; Okawa, Y ; Gorgun, G ; Perrone, G ; Calabrese, E ; Yule, M ; Squires, M ; Ladetto, M ; Boccadoro, M ; Richardson, P G ; Munshi, N C ; Anderson, K C ; Raje, N
Publisher:England
Journal title:Oncogene, 2010-04, Vol.29 (16), p.2325
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Lenalidomide for the treatment of relapsed and refractory multiple myeloma
Author / Creator:Gorgun, Gullu ; Van De Donk ; Groen ; Jakubikova ; Mitsiades, Constantine ; Hideshima, Teru ; Richardson, Paul ; Nijhof ; Raymakers ; Lokhorst, H ; Anderson ; Laubach, Jacob
Publisher:New Zealand: Dove Medical Press Limited
Journal title:Cancer management and research, 2012, Vol.4, p.253-268
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Showing 1 to 20 of 20 results

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Histone deacetylase 3 as a novel therapeutic target in multiple myeloma

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Class IIa HDAC inhibition enhances ER stress-mediated cell death in multiple myeloma

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Ascorbic acid inhibits antitumor activity of bortezomib in vivo

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AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3β activation and RNA polymerase II inhibition

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Small-molecule multi-targeted kinase inhibitor RGB-286638 triggers P53-dependent and -independent anti-multiple myeloma activity through inhibition of transcriptional CDKs

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Rational combination treatment with histone deacetylase inhibitors and immunomodulatory drugs in multiple myeloma

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Anti-tumor activities of selective HSP90α/β inhibitor, TAS-116, in combination with bortezomib in multiple myeloma

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Induction of differential apoptotic pathways in multiple myeloma cells by class-selective histone deacetylase inhibitors

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A novel reduced intensity regimen for allogeneic hematopoietic stem cell transplantation associated with a reduced incidence of graft-versus-host disease

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Chronic lymphocytic leukemia cells induce changes in gene expression of CD4 and CD8 T cells

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A novel rapid-onset high-penetrance plasmacytoma mouse model driven by deregulation of cMYC cooperating with KRAS12V in BALB/c mice

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Anti-tumor activities of selective HSP90[alpha]/[beta] inhibitor, TAS-116, in combination with bortezomib in multiple myeloma

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AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3b activation and RNA polymerase II inhibition

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AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3[beta] activation and RNA polymerase II inhibition

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Extracorporeal photopheresis in chronic graft-versus-host disease

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Extracorporeal photopheresis in chronic graft-versus-host disease: Mini-Review

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Extracorporeal photopheresis in chronic graft-versus-host disease

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A novel reduced intensity regimen for allogeneic hematopoietic stem cell transplantation associated with a reduced incidence of graft-versus-host disease: Reduced Intensity Conditioning Regimens

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AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3beta activation and RNA polymerase II inhibition

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Lenalidomide for the treatment of relapsed and refractory multiple myeloma

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