Silymarin and silibinin cause G1 and G2–M cell cycle arrest via distinct circuitries in human prosta...
Silymarin and silibinin cause G1 and G2–M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin
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Author / Creator
Deep, G , Singh, R P , Agarwal, C , Kroll, D J and Agarwal, R
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Here, we assessed and compared the anticancer efficacy and associated mechanisms of silymarin and silibinin in human prostate cancer (PCA) PC3 cells; silymarin is comprised of silibinin and its other stereoisomers, including isosilybin A, isosilybin B, silydianin, silychristin and isosilychristin. Silymarin and silibinin (50–100
μ
g/ml) inhi...
Alternative Titles
Full title
Silymarin and silibinin cause G1 and G2–M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin
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Record Identifier
TN_cdi_proquest_miscellaneous_67668096
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67668096
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1209146
