Regulation of cancer cell migration and bone metastasis by RANKL
Regulation of cancer cell migration and bone metastasis by RANKL
About this item
Full title
Author / Creator
Jones, D. Holstead , Nakashima, Tomoki , Sanchez, Otto H. , Kozieradzki, Ivona , Komarova, Svetlana V. , Sarosi, Ildiko , Morony, Sean , Rubin, Evelyn , Sarao, Renu , Hojilla, Carlo V. , Komnenovic, Vukoslav , Kong, Young-Yun , Schreiber, Martin , Dixon, S. Jeffrey , Sims, Stephen M. , Khokha, Rama , Wada, Teiji and Penninger, Josef M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Cancer cells that express the receptor protein RANK migrate to bone tissue where the RANK ligand, RANKL, is found. This contributes to bone metastases and offers a potential therapeutic approach to prevent cancer metastases.
Bone metastases are a frequent complication of many cancers that result in severe disease burden and pain
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Alternative Titles
Full title
Regulation of cancer cell migration and bone metastasis by RANKL
Authors, Artists and Contributors
Author / Creator
Nakashima, Tomoki
Sanchez, Otto H.
Kozieradzki, Ivona
Komarova, Svetlana V.
Sarosi, Ildiko
Morony, Sean
Rubin, Evelyn
Sarao, Renu
Hojilla, Carlo V.
Komnenovic, Vukoslav
Kong, Young-Yun
Schreiber, Martin
Dixon, S. Jeffrey
Sims, Stephen M.
Khokha, Rama
Wada, Teiji
Penninger, Josef M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_67811948
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67811948
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687,1476-4679
DOI
10.1038/nature04524
