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Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus t...

Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus t...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67839820

Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I

About this item

Full title

Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2006-04, Vol.12 (4), p.466-472

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Adult T-cell leukemia-lymphoma (ATLL) is a group of T-cell malignancies caused by infection with human T-lymphotropic virus type I (HTLV-I). Although the pathogenesis of ATLL remains incompletely understood, the viral regulatory protein Tax is centrally involved in cellular transformation. Here we describe the generation of HTLV-I Tax transgenic mi...

Alternative Titles

Full title

Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67839820

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67839820

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm1389

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