The Activating NKG2D Receptor Assembles in the Membrane with Two Signaling Dimers into a Hexameric S...
The Activating NKG2D Receptor Assembles in the Membrane with Two Signaling Dimers into a Hexameric Structure
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The activating NKG2D receptor plays a critical role in innate and adaptive immune responses by natural killer cells and subpopulations of T cells. The human receptor assembles with the DAP10 signaling dimer, and it is thought that one NKG2D homodimer pairs with a single DAP10 dimer by formation of two salt bridges between charged transmembrane (TM)...
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Full title
The Activating NKG2D Receptor Assembles in the Membrane with Two Signaling Dimers into a Hexameric Structure
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TN_cdi_proquest_miscellaneous_67864951
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67864951
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0502439102
