Antisense therapy for cancer
Antisense therapy for cancer
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
Antisense oligonucleotides (ASOs) offer one approach to target genes involved in cancer progression, particularly those that are not amenable to small-molecule or antibody inhibition.
ASOs inhibit translation through a mechanism that involves the formation of an mRNA–ASO duplex, leading to RNase-H-mediated cleavage of the target mR...
Alternative Titles
Full title
Antisense therapy for cancer
Authors, Artists and Contributors
Author / Creator
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TN_cdi_proquest_miscellaneous_67894342
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67894342
Other Identifiers
ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc1631
