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The Small Antitumoral Immune Response Modifier Imiquimod Interacts with Adenosine Receptor Signaling...

The Small Antitumoral Immune Response Modifier Imiquimod Interacts with Adenosine Receptor Signaling...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67976448

The Small Antitumoral Immune Response Modifier Imiquimod Interacts with Adenosine Receptor Signaling in a TLR7- and TLR8-Independent Fashion

About this item

Full title

The Small Antitumoral Immune Response Modifier Imiquimod Interacts with Adenosine Receptor Signaling in a TLR7- and TLR8-Independent Fashion

Publisher

Danvers, MA: Elsevier Inc

Journal title

Journal of investigative dermatology, 2006-06, Vol.126 (6), p.1338-1347

Language

English

Formats

Publication information

Publisher

Danvers, MA: Elsevier Inc

More information

Scope and Contents

Contents

Imiquimod, a small-molecule immune response modifier of the imidazoquinoline family, has shown profound antitumoral and antiviral efficacy both in vitro and in clinical applications in vivo. It has been demonstrated that this activity is mediated through the Toll-like receptor (TLR)7- and TLR8-signaling cascade resulting in the secretion of proinfl...

Alternative Titles

Full title

The Small Antitumoral Immune Response Modifier Imiquimod Interacts with Adenosine Receptor Signaling in a TLR7- and TLR8-Independent Fashion

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67976448

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67976448

Other Identifiers

ISSN

0022-202X

E-ISSN

1523-1747

DOI

10.1038/sj.jid.5700286

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