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Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts

Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67987541

Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts

About this item

Full title

Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts

Publisher

New York: Nature Publishing Group US

Journal title

Nature Immunology, 2006-06, Vol.7 (6), p.652-662

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The induction of alloantigen-specific unresponsiveness remains an elusive goal in organ transplantation. Here we identify plasmacytoid dendritic cells (pDCs) as phagocytic antigen-presenting cells essential for tolerance to vascularized cardiac allografts. Tolerizing pDCs acquired alloantigen in the allograft and then moved through the blood to hom...

Alternative Titles

Full title

Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67987541

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67987541

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916,1365-2567

DOI

10.1038/ni1333

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