Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts
Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Contents
The induction of alloantigen-specific unresponsiveness remains an elusive goal in organ transplantation. Here we identify plasmacytoid dendritic cells (pDCs) as phagocytic antigen-presenting cells essential for tolerance to vascularized cardiac allografts. Tolerizing pDCs acquired alloantigen in the allograft and then moved through the blood to hom...
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Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts
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TN_cdi_proquest_miscellaneous_67987541
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67987541
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ISSN
1529-2908
E-ISSN
1529-2916,1365-2567
DOI
10.1038/ni1333