Telomere protection by mammalian Pot1 requires interaction with Tpp1
Telomere protection by mammalian Pot1 requires interaction with Tpp1
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The shelterin complex at mammalian telomeres contains the single-stranded DNA–binding protein Pot1, which regulates telomere length and protects chromosome ends. Pot1 binds Tpp1, the shelterin component that connects Pot1 to the duplex telomeric DNA–binding proteins Trf1 and Trf2. Control of telomere length requires that Pot1 binds Tpp1 as well as...
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Full title
Telomere protection by mammalian Pot1 requires interaction with Tpp1
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TN_cdi_proquest_miscellaneous_68126347
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68126347
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb1270
