Characterization of a radiolabeled small molecule targeting leukocyte function-associated antigen-1...
Characterization of a radiolabeled small molecule targeting leukocyte function-associated antigen-1 expression in lymphoma and leukemia
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Publisher
United States: Mary Ann Liebert, Inc
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Language
English
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Publisher
United States: Mary Ann Liebert, Inc
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Contents
Leukocyte function-associated antigen-1 (LFA-1) is constitutively expressed on leukocytes, including overexpression on lymphomas and leukemias. We have developed a derivative of BIRT 377, an allosteric inhibitor of LFA-1, which may be chemically tagged without affecting binding. In this study, we modified this derivative, (R)-1-(4-aminobutyl)-5-(4-...
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Full title
Characterization of a radiolabeled small molecule targeting leukocyte function-associated antigen-1 expression in lymphoma and leukemia
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TN_cdi_proquest_miscellaneous_68148569
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68148569
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ISSN
1084-9785
E-ISSN
1557-8852
DOI
10.1089/cbr.2006.21.418
