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Characterization of a radiolabeled small molecule targeting leukocyte function-associated antigen-1...

Characterization of a radiolabeled small molecule targeting leukocyte function-associated antigen-1...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68148569

Characterization of a radiolabeled small molecule targeting leukocyte function-associated antigen-1 expression in lymphoma and leukemia

About this item

Full title

Characterization of a radiolabeled small molecule targeting leukocyte function-associated antigen-1 expression in lymphoma and leukemia

Publisher

United States: Mary Ann Liebert, Inc

Journal title

Cancer biotherapy & radiopharmaceuticals, 2006-10, Vol.21 (5), p.418-426

Language

English

Formats

Publication information

Publisher

United States: Mary Ann Liebert, Inc

More information

Scope and Contents

Contents

Leukocyte function-associated antigen-1 (LFA-1) is constitutively expressed on leukocytes, including overexpression on lymphomas and leukemias. We have developed a derivative of BIRT 377, an allosteric inhibitor of LFA-1, which may be chemically tagged without affecting binding. In this study, we modified this derivative, (R)-1-(4-aminobutyl)-5-(4-...

Alternative Titles

Full title

Characterization of a radiolabeled small molecule targeting leukocyte function-associated antigen-1 expression in lymphoma and leukemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68148569

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68148569

Other Identifiers

ISSN

1084-9785

E-ISSN

1557-8852

DOI

10.1089/cbr.2006.21.418

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