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A transglutaminase homologue as a condensation catalyst in antibiotic assembly lines

A transglutaminase homologue as a condensation catalyst in antibiotic assembly lines

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68172496

A transglutaminase homologue as a condensation catalyst in antibiotic assembly lines

About this item

Full title

A transglutaminase homologue as a condensation catalyst in antibiotic assembly lines

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2007-08, Vol.448 (7155), p.824-827

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

A new line in antibiotics
Andrimid is a hybrid nonribosomal peptide-polyketide antibiotic that has been isolated from several different types of bacteria in the past twenty years. It is a nanomolar inhibitor of bacterial acetyl-CoA carboxylase, and inhibiting this enzyme blocks a step in prokaryotic fatty acid biosynthesis. Fortin
et al
....

Alternative Titles

Full title

A transglutaminase homologue as a condensation catalyst in antibiotic assembly lines

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68172496

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68172496

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature06068

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