Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury
Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Neurotrophins are essential for development and maintenance of the vertebrate nervous system. Paradoxically, although mature neurotrophins promote neuronal survival by binding to tropomyosin receptor kinases and p75 neurotrophin receptor (p75
NTR
), pro-neurotrophins induce apoptosis in cultured neurons by engaging sortilin and p75
NTR
...
Alternative Titles
Full title
Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury
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Record Identifier
TN_cdi_proquest_miscellaneous_68444386
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68444386
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn2000
