Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation
Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Human and mouse genetic and
in vitro
evidence has shown that canonical Wnt signaling promotes bone formation, but we found that mice lacking the canonical Wnt antagonist Dickkopf2 (Dkk2) were osteopenic. We reaffirmed the finding that canonical Wnt signaling stimulates osteogenesis, including the differentiation from preosteoblasts to osteobl...
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Full title
Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation
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TN_cdi_proquest_miscellaneous_68536206
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68536206
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng1614
