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Oncogenic CARD11 Mutations in Human Diffuse Large B Cell Lymphoma

Oncogenic CARD11 Mutations in Human Diffuse Large B Cell Lymphoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68563646

Oncogenic CARD11 Mutations in Human Diffuse Large B Cell Lymphoma

About this item

Full title

Oncogenic CARD11 Mutations in Human Diffuse Large B Cell Lymphoma

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2008-03, Vol.319 (5870), p.1676-1679

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Diffuse large B cell lymphoma (DLBCL) is the most common form of non-Hodgkin's lymphoma. In the least curable (ABC) subtype of DLBCL, survival of the malignant cells is dependent on constitutive activation of the nuclear factor-κB (NF-κB) signaling pathway. In normal B cells, antigen receptor-induced NF-κB activation requires CARD11, a cytoplasmic...

Alternative Titles

Full title

Oncogenic CARD11 Mutations in Human Diffuse Large B Cell Lymphoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68563646

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68563646

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1153629

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