HST2 Mediates SIR2-Independent Life-Span Extension by Calorie Restriction
HST2 Mediates SIR2-Independent Life-Span Extension by Calorie Restriction
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Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Contents
Calorie restriction (CR) extends the life span of numerous species, from yeast to rodents. Yeast Sir2 is a nicotinamide adenine dinucleotide (NAD⁺-dependent histone deacetylase that has been proposed to mediate the effects of CR. However, this hypothesis has been challenged by the observation that CR can extend yeast life span in the absence of Sir...
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Full title
HST2 Mediates SIR2-Independent Life-Span Extension by Calorie Restriction
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TN_cdi_proquest_miscellaneous_68592941
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68592941
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1113611
