Nogo-A–specific antibody treatment enhances sprouting and functional recovery after cervical lesion...
Nogo-A–specific antibody treatment enhances sprouting and functional recovery after cervical lesion in adult primates
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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In rodents, after spinal lesion, neutralizing the neurite growth inhibitor Nogo-A promotes axonal sprouting and functional recovery. To evaluate this treatment in primates, 12 monkeys were subjected to cervical lesion. Recovery of manual dexterity and sprouting of corticospinal axons were enhanced in monkeys treated with Nogo-A–specific antibody as...
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Full title
Nogo-A–specific antibody treatment enhances sprouting and functional recovery after cervical lesion in adult primates
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TN_cdi_proquest_miscellaneous_68629523
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68629523
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm1436
